Better diagnostics

start here.

 
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WHAT WE OFFER

realSENSe: The most accurate diagnostic test for patients suffering from Urinary Tract Infections (UTIs), cystitis, prostatitis or other types of infections associated with bacteria in the Urinary Tract (UT). realSENSe’s state of the art Antimicrobial Susceptibility Testing (AST) produces personalized treatment options so clinicians can prescribe with confidence.

 

WHO IT HELPS (by %)

 

SPECIALTIES MOST BENEFITED (by %)

 

Microbiology:

The evolution.

Since the 1950s, urine culture has been the gold standard for diagnosing Urinary Tract Infections (UTI). Although molecular diagnostic approaches with their DNA amplification techniques have replaced outdated diagnosis methods for some infections, UTIs are still generally diagnosed as they have been for decades - by urine culture.

Standard culture presents significant limitations for detection of the full spectrum of urinary bacterial species due to slow growing bacteria that die in the presence of oxygen. Faster and more accurate diagnostic methods are available today but, there is still a missing component to begin defining a cure - Effective Antimicrobial Susceptibility Testing (AST).

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The new gold standard -

Molecular UTI diagnostics via Polymerase Chain Reaction (PCR) + Comprehensive AST


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The human microbiome is comprised of complex and dynamic microbial communities. It is more likely that the community characteristics, such as composition and metagenomic functionality are responsible for disease development as opposed to single organisms, thus, proving urine culture to be an extremely ineffective method of diagnosis. Over the past decade, the study of the human microbiome and its relation to health and disease has flourished due to the technological advances of microbiology testing. Source

Most PCR-based diagnostic efforts focus heavily on defining optimal uropathogen colony counts to diagnose UTIs. Meanwhile, very minimal diagnostic efforts are devoted to identifying a specific antibiotic treatment to eradicate the infection. Source


Culture vs. PCR


67+

Percent of uropathogens

67% of uropathogens are missed with standard urine culture and 50% in patients with severe urinary symptoms.

Fact check.

 
 

150+

Million people affected

UTIs are some of the most common bacterial infections, affecting 150 million people each year worldwide.

Fact check.

80+

Percent of cultures are negative

Studies have shown that depending on the population, up to 80% of urine cultures are negative, underlining the need for more effective methods of diagnosis.

Fact check.


The necessity for PCR-based diagnostics


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Sensitivity

Standard urine culture misses 67% of uropathogens overall. Molecular PCR testing identifies significant bacteriuria resulting in a sensitivity of 97%.

Sensitivity


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Speed

Due to slow growth with standard urine culture, turnaround time can be anywhere from 24 hours to 120 hours.

Molecular PCR testing will produce results in 24 hours or less if negative and if positive, within 48 hours or less including Antimicrobial Susceptibility Testing (AST).

Turnaround Time


 
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Polymicrobial

An estimated 33% of urine cultures from elderly patients are polymicrobial. Cultures only identify pathogens in mixed cultures if there is a significant count of a predominant organism. Most are reported as “mixed flora”.

UTIs account for 20-60% of all antibiotic prescription use in long-term care facilities, contributing to antibiotic resistance in urinary pathogens. PCR + AST will identify and quantify ALL pathogens and provide effective treatment recommendations every time.

Annual Incidence of UTI in Elderly

Morbidity and mortality percentages of elderly population (age >60)

 

The most accurate diagnostic test:

realSENSe

When patients need solutions fast, clinicians trust the diagnostic precision and personalized Antimicrobial Susceptibility Testing (AST) of realSENSe. Our robust test identifies 20+ gram-positive, gram-negative, and fungi organisms and uses a pooled phenotypic testing methodology to generate personalized treatment plans for every patient within 24-48 hours.

 
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PCR + Antimicrobial Susceptibility Testing (AST)

How Real Diagnostics helps combat Antibiotic Resistance

 
Negative test results are available within 24 hours and positive results are available within 48 hours complete with antibiotic recommendations.

Negative test results are available within 24 hours and positive results are available within 48 hours complete with antibiotic recommendations.

realSENSe can identify up to 24 pathogens and precise bacterial count using Real-time PCR DNA analysis.

realSENSe can identify up to 24 pathogens and precise bacterial count using Real-time PCR DNA analysis.

Our unique approach uses pooled phenotypic testing AND identification of key genotype resistance markers to determine antimicrobial susceptibility.

Our unique approach uses pooled phenotypic testing AND identification of key genotype resistance markers to determine antimicrobial susceptibility.

 
 
realSENSe accurately diagnose and reports a definitive treatment recommendation for each individual patient.

realSENSe accurately diagnose and reports a definitive treatment recommendation for each individual patient.

 

Real results. Real solutions.

realSENSe is the ultimate solution for clinicians with patients suffering from Urinary Tract Infections (UTIs), cystitis, prostatitis or other types of infections associated with bacteria in the Urinary Tract (UT). Our test offers unmatched accuracy and efficiency for patients with monomicrobial or polymicrobial infections.

 
 

 Your patients deserve REAL answers.

Choose the clear path to a REAL recovery.

 
 
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